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Predator-Prey Simulation in JavaScript
Méry, Jozef ; Janoušek, Vladimír (referee) ; Peringer, Petr (advisor)
Študovanie populácie organizmov je veľmi užitočná oblasť výskumu. Dokáže pomôcť s predpovedaním, porozumením a možným zachovaním populácií. Táto bakalárska práca sa zameriava na modelovanie a simulovanie modelu dravec-korisť založeného na agentoch. Medzi najpodstatnejšie vlastnosti agentov patrí schopnosť zhlukovania založená na modeli boids vytvorený C. Reynoldsom, reprodukcia a mutácia. Výsledok tejto práce je konfigurovateľná prehliadačová aplikácia, ktorú možno použiť na simulovanie rôzných situácií a získanie štatistických údajov. Aplikácia obsahuje šablóny nastavení, ktoré boli simulované. Výsledky simulácií sú krátko zhodnotené.
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The prevalence of chosen polymorphisms of luteinizing hormone receptor gene in Czech population and patients with ovarian hyperstimulation syndrome
Chrudimská, Jana ; Macek, Milan (advisor) ; Schierová, Michaela (referee)
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic potentially life-threatening complication of assisted reproduction techniques (ART). It is caused by an increased sensitivity of ovaries to gonadotropins administered during the controlled ovarian hyperstimulation (COH). Thus, the degree of ovarian response can be gently tuned by genetic polymorphisms of gonadotropins and their receptors. The aim of this study is to ascertain the prevalence of polymorphisms Asn291Ser (rs1470652), Ser312Asn (rs2293275) and insLQ (insertion of leucine and glutamine, rs58356637) in the luteinizing hormone chorionic gonadotropin receptor (LHCGR) gene in 102 Czech fertile men, 149 fertile women and 58 patients with serious grade of OHSS. Detection of the Asn291Ser and Ser312Asn polymorphisms was performed using TaqMan SNP Genotyping Assays. The insLQ variation was detected by the capillary electrophoresis with fluorescence-labeled primers. This study ascertained the prevalence of studied variants in Czech fertile population. Obtained results are in concordance with the majority of data from other European populations. There is no difference in prevalence between control-men and control-women. No relation to the development of OHSS was disclosed. The number of analyzed samples is too small for haplotype analysis. These...
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Role of polymorphic DNA markers in personal identification and determination of selected phenotypic traits
Zidkova, Anastassiya ; Korabečná, Marie (advisor) ; Drábek, Jiří (referee) ; Hradil, Roman (referee)
Nowadays intensive research is conducted for application of genetic polymorphisms for degraded samples analysis, identification and kinship determination. Another area of research in forensic genetics is biogeographical and phenotypic traits (eye, hair and skin color) determination. First part of presented work dealt with population study on the Czech popu- lation using Investigator DIPplex (QIAGEN, Germany) marker set containing 30 autosomal insertion-deletion polymorphisms. Power of Discrimination (PD), which is the probability of random selection of two persons with different genotypes, was 99.9999999999% for the whole marker set. This part of study concluded that ana- lyzed marker set is suitable as an additional marker panel for identification and kinship determination in the Czech Republic. Second part of the presented study was devoted to population research of Cen- tral Croatia using Mentype Argus X-8 kit (QIAGEN, Germany) containing 8 short tandem repeat polymorhisms located on X choromosomes (X-STR) divided into 4 linkage groups. PD for the whole kit reached 99.9999% and 99.99999999% for males and females, respectively. This kit could be used in Central Croatian population for kinship analysis and for identification as an additional marker panel. The next part of the presented study was the...
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Predator-Prey Simulation in JavaScript
Méry, Jozef ; Janoušek, Vladimír (referee) ; Peringer, Petr (advisor)
Študovanie populácie organizmov je veľmi užitočná oblasť výskumu. Dokáže pomôcť s predpovedaním, porozumením a možným zachovaním populácií. Táto bakalárska práca sa zameriava na modelovanie a simulovanie modelu dravec-korisť založeného na agentoch. Medzi najpodstatnejšie vlastnosti agentov patrí schopnosť zhlukovania založená na modeli boids vytvorený C. Reynoldsom, reprodukcia a mutácia. Výsledok tejto práce je konfigurovateľná prehliadačová aplikácia, ktorú možno použiť na simulovanie rôzných situácií a získanie štatistických údajov. Aplikácia obsahuje šablóny nastavení, ktoré boli simulované. Výsledky simulácií sú krátko zhodnotené.
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Role of polymorphic DNA markers in personal identification and determination of selected phenotypic traits
Zidkova, Anastassiya ; Korabečná, Marie (advisor) ; Drábek, Jiří (referee) ; Hradil, Roman (referee)
Nowadays intensive research is conducted for application of genetic polymorphisms for degraded samples analysis, identification and kinship determination. Another area of research in forensic genetics is biogeographical and phenotypic traits (eye, hair and skin color) determination. First part of presented work dealt with population study on the Czech popu- lation using Investigator DIPplex (QIAGEN, Germany) marker set containing 30 autosomal insertion-deletion polymorphisms. Power of Discrimination (PD), which is the probability of random selection of two persons with different genotypes, was 99.9999999999% for the whole marker set. This part of study concluded that ana- lyzed marker set is suitable as an additional marker panel for identification and kinship determination in the Czech Republic. Second part of the presented study was devoted to population research of Cen- tral Croatia using Mentype Argus X-8 kit (QIAGEN, Germany) containing 8 short tandem repeat polymorhisms located on X choromosomes (X-STR) divided into 4 linkage groups. PD for the whole kit reached 99.9999% and 99.99999999% for males and females, respectively. This kit could be used in Central Croatian population for kinship analysis and for identification as an additional marker panel. The next part of the presented study was the...
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The prevalence of chosen polymorphisms of luteinizing hormone receptor gene in Czech population and patients with ovarian hyperstimulation syndrome
Chrudimská, Jana ; Macek, Milan (advisor) ; Schierová, Michaela (referee)
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic potentially life-threatening complication of assisted reproduction techniques (ART). It is caused by an increased sensitivity of ovaries to gonadotropins administered during the controlled ovarian hyperstimulation (COH). Thus, the degree of ovarian response can be gently tuned by genetic polymorphisms of gonadotropins and their receptors. The aim of this study is to ascertain the prevalence of polymorphisms Asn291Ser (rs1470652), Ser312Asn (rs2293275) and insLQ (insertion of leucine and glutamine, rs58356637) in the luteinizing hormone chorionic gonadotropin receptor (LHCGR) gene in 102 Czech fertile men, 149 fertile women and 58 patients with serious grade of OHSS. Detection of the Asn291Ser and Ser312Asn polymorphisms was performed using TaqMan SNP Genotyping Assays. The insLQ variation was detected by the capillary electrophoresis with fluorescence-labeled primers. This study ascertained the prevalence of studied variants in Czech fertile population. Obtained results are in concordance with the majority of data from other European populations. There is no difference in prevalence between control-men and control-women. No relation to the development of OHSS was disclosed. The number of analyzed samples is too small for haplotype analysis. These...
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